PN-IV-P2-2.1-TE-2023-0525

The cognitive and socio-economic impact of colon cancer

Each person's experience with cancer is unique. No two people experience it in the same way. As a result, it is challenging to completely comprehend the whole range of physical, mental, and social effects that a cancer diagnosis has on each person.

Tumor biomarkers are substances (such as proteins, hormones, or genetic mutations) produced by cancer cells or by the body in response to their presence, used for diagnosis, monitoring, and personalization of treatment. Their presence in biological fluids or tissues can provide essential information for clinical screening initiatives and early detection of cancer, which, in terms of the economy’s perspective, leads to substantial cost benefits for society and health systems. Consequently, the need for reliable analytical methodologies for the detection of tumor biomarkers in the early stages of carcinogenesis is extremely important.

The main objective of this project is to discover new biomarkers related to colon cancer and validate the technology at the laboratory level using biological samples. These tumor markers facilitate early detection of cancer, when the chances of treatment are higher. Stochastic sensors are a favorable alternative to traditional electrochemical sensors and chromatographic methods. They can determine both the quality and quantity of several analytes at the same time in a single test. Stochastic sensors are suitable for screening biological samples because they can detect a wide range of concentrations, have low detection limits, and can simultaneously measure a panel of biomarkers.

Stages of colon cancer development in the human body

National Project

Young Teams 115TE/2025

New electrochemical sensing platforms based on carbon nanodots and metallic nanoparticles for early CRC screening